Anemarrhena Extract Powder

Latin Origin: Anemarrhena asphodeloides Bge.
Other names: Anemarrhena extract; anemarrhenae extract; Anemarrhena Rhizome Extract; Rhizoma Anemarrhenae extract; Anemarrhenia artemisiae extract; Anemarhenae Asphodeliodes Extract
Appearance: Yellow-brown Fine Powder
Specification: 5:1; 10:1; 20:1
Active Ingredients: steroidal saponins, phenylpropanoids, and polysaccharides


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Product Introduction

Anemarrhena Extract Powder is derived from the plant Anemarrhena asphodeloides, which belongs to the family Asparagaceae. The active ingredients in Anemarrhena Extract Powder include steroidal saponins, phenylpropanoids, and polysaccharides. These active components are responsible for the various pharmacological effects of Anemarrhena Extract Powder, such as anti-ulcer, antibacterial, antipyretic, adrenal protection, modulation of brain and myocardial cell receptors, improvement of learning and memory function, antiplatelet aggregation, hypoglycemic, and other effects.
The plant Anemarrhena asphodeloides is also known by various other names such as common anemarrhena, Zhi Mu, Lian Mu, Ye Liao, Di Shen, Shui Shen, Ku Xin, Chang Zhi, Mao Zhi Mu, Fei Zhi Mu, Suan Ban Zi Cao, Yang Hu Zi Gen, and others. The plant’s rhizome is the primary source of the extract, and it is commonly found in regions such as Hebei, Shanxi, Shaanxi, and Inner Mongolia. It is a commonly used medicinal herb in China, with a history that stretches back more than 2,000 years.
The extract is prepared by processing the rhizome, and it contains various bioactive compounds including Anemarrhena saponins, Anemarrhena polysaccharides, flavonoids such as mangiferin, as well as trace elements like iron, zinc, manganese, copper, chromium, and nickel. Additionally, it contains β-sitosterol, Anemarrhena fat A, lignans, alkaloids, choline, tannic acid, niacin, and other components.
These active ingredients contribute to the diverse pharmacological effects of Anemarrhena Extract Powder, making it a valuable natural product with potential therapeutic applications.

Specification(COA)

Main Active Ingredients in Chinese English Name CAS No. Molecular Weight Molecular Formula
乙酰知母皂苷元 Smilagenin acetate 4947-75-5 458.67 C29H46O4
知母皂苷A2 Anemarrhenasaponin A2 117210-12-5 756.92 C39H64O14
知母皂苷III Anemarrhenasaponin III 163047-23-2 756.92 C39H64O14
知母皂苷I Anemarrhenasaponin I 163047-21-0 758.93 C39H66O14
知母皂苷Ia Anemarrhenasaponin Ia 221317-02-8 772.96 C40H68O14
新知母皂苷BII Officinalisinin I 57944-18-0 921.07 C45H76O19
知母皂苷C Timosaponin C 185432-00-2 903.06 C45H74O18
知母皂苷E Anemarsaponin E 136565-73-6 935.1 C46H78O19
知母皂苷 BIII Anemarsaponin BIII 142759-74-8 903.06 C45H74O18
异芒果苷 Isomangiferin 24699-16-9 422.34 C19H18O11
L-缬氨酸 L-Valine 72-18-4 117.15 C5H11NO2
知母皂苷A1 Timosaponin A1 68422-00-4 578.78 C33H54O8
知母皂苷 A-III Timosaponin A3 41059-79-4 740.92 C39H64O13
知母皂苷 B II Timosaponin BII 136656-07-0 921.07 C45H76O19
新芒果苷 Neomangiferin 64809-67-2 584.48 C25H28O16
芒果苷 Mangiferin 4773-96-0 422.34 C19H18O11
菝葜皂苷元 Sarsasapogenin 126-19-2 416.64 C27H44O3
牡荆素 Vitexin 3681-93-4 432.38 C21H20O10

 

Items Standards Results
Physical Analysis
Description Brown Fine Powder Complies
Assay 10:1 Complies
Mesh Size 100 % pass 80 mesh Complies
Ash ≤ 5.0% 2.85%
Loss on Drying ≤ 5.0% 2.85%
Chemical Analysis
Heavy Metal ≤ 10.0 mg/kg Complies
Pb ≤ 2.0 mg/kg Complies
As ≤ 1.0 mg/kg Complies
Hg ≤ 0.1 mg/kg Complies
Microbiological Analysis
Residue of Pesticide Negative Negative
Total Plate Count ≤ 1000cfu/g Complies
Yeast&Mold ≤ 100cfu/g Complies
E.coil Negative Negative
Salmonella Negative Negative

Product Features/ Health Benefits

Anemarrhena Extract is derived from the plant Anemarrhena asphodeloides and is known for its diverse pharmacological effects and potential therapeutic applications. The product features and functions of Anemarrhena Extract include:
1. Anti-ulcer properties, effective in inhibiting stress-induced ulcers.
2. Antibacterial activity against various pathogens including Shigella, Salmonella, Vibrio cholerae, Escherichia coli, Streptococcus, Staphylococcus, and Candida species.
3. Antipyretic effect, useful in reducing fever.
4. Adrenal protection, demonstrated by its ability to counteract the suppressive effects of dexamethasone on plasma cortisol levels and prevent adrenal atrophy.
5. Modulation of brain and myocardial cell receptors, potentially influencing neurotransmitter activity and cardiac function.
6. Improvement of learning and memory function, as evidenced by enhanced cognitive abilities in animal studies.
7. Antiplatelet aggregation, attributed to specific active components such as Anemarrhena saponins.
8. Influence on hormone activity, including the ability to counteract the inhibitory effects of dexamethasone on plasma corticosterone levels.
9. Hypoglycemic effects, demonstrated by its ability to lower blood glucose levels in normal and diabetic animal models.
10. Inhibition of aldose reductase, potentially delaying the onset of diabetic cataracts.
11. Other bioactive components such as flavonoids, trace elements, sterols, lignans, alkaloids, choline, tannic acid, niacin, and more contribute to its overall pharmacological profile.

Applications

Anemarrhena Extract has applications in various industries, including:
1. Pharmaceutical industry for developing anti-ulcer, antibacterial, and antipyretic medications.
2.  Nutraceutical and dietary supplement industry for its potential adrenal protection and hypoglycemic properties.
3.  Cosmetics industry for potential skin health benefits due to its antibacterial and anti-inflammatory properties.
4.  Herbal medicine industry for traditional uses in addressing fever, respiratory conditions, and diabetes.
5.  Research and development for investigating its effects on brain function, memory enhancement, and platelet aggregation.
6. Food and beverage industry for potential use in functional foods and beverages targeting blood sugar management and immune support.

Pharmacological Properties and Cosmetic Applications

Anemarrhena asphodeloides (A. asphodeloides) root extract exhibits antipyretic, cardiotonic, diuretic, antibacterial, muco-active, sedative, hypoglycemic, and anticarcinogenic properties. The rootstock, the main component of A. asphodeloides, contains about 6% saponins, including steroid saponins such as timosaponin A-I, A-III, B-II, anemarsaponin B, F-gitonin, smilageninoside, degalactotigonin, and nyasol. Among these, timosaponin A-III demonstrates anticarcinogenic and hypoglycemic effects. Additionally, A. asphodeloides contains polyphenol compounds like mangiferin, isomangiferin, and neomangiferin, which are xanthone derivatives. The rootstock also contains roughly 0.5% mangiferin (chimonin), known for its antidiabetic properties. A. asphodeloides is extensively used as herbal medicine in China, Japan, and Korea, where it is cultivated and processed as a primary raw material. It is listed as “Anemarrhena asphodeloides root extract” (AARE) in the Korean standards for cosmetic ingredients and in the International Cosmetic Ingredient Dictionary and Handbook. A. asphodeloides is recognized as a cosmetic raw material, with Volufiline™ from the French company Sederma being a popular choice due to its high sarasapogenin content, which has diverse pharmaceutical applications.

Potential Side Effects

Anemarrhena Extract is generally considered safe when used appropriately. However, as with any natural product or medication, there is a potential for side effects, especially when used in excessive amounts or in sensitive individuals. Some potential side effects of Anemarrhena Extract may include:
Gastrointestinal discomfort: Some individuals may experience digestive issues such as nausea, vomiting, or diarrhea.
Allergic reactions:  People with known allergies to plants in the Asparagaceae family may experience allergic reactions to Anemarrhena Extract.
Drug interactions: Anemarrhena Extract may interact with certain medications, particularly those affecting blood sugar levels or blood clotting. It is important to consult a healthcare professional before using it in combination with other medications.
Pregnancy and breastfeeding: There is limited information on the safety of Anemarrhena Extract during pregnancy and breastfeeding, so it is advisable for pregnant or nursing women to exercise caution and seek medical advice before use.
It’s important to consult a healthcare professional before using Anemarrhena Extract, especially if you have any underlying health conditions or are taking medications, to minimize the risk of potential side effects and interactions.


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  • Packaging And Service

    Packaging
    * Delivery Time: Around 3-5 workdays after your payment.
    * Package: In fiber drums with two plastic bags inside.
    * Net Weight: 25kgs/drum,Gross Weight: 28kgs/Drum
    * Drum Size & Volume: I.D.42cm × H52cm, 0.08 m³/ Drum
    * Storage: Stored in a dry and cool place, keep away from strong light and heat.
    * Shelf Life: Two years when properly stored.

    Shipping
    * DHL Express, FEDEX, and EMS for quantities less than 50KG, usually called as DDU service.
    * Sea shipping for quantities over 500 kg; and air shipping is available for 50 kg above.
    * For high-value products, please select air shipping and DHL express for safety.
    * Please confirm if you can make the clearance when goods reach your customs before placing an order. For buyers from Mexico, Turkey, Italy, Romania, Russia, and other remote areas.

    bioway packings for plant extract

    Payment And Delivery Methods

    Express
    Under 100kg, 3-5 Days
    Door to door service easy to pick up the goods

    By Sea
    Over300kg, Around 30 Days
    Port to port service professional clearance broker needed

    By Air
    100kg-1000kg, 5-7 Days
    Airport to airport service professional clearance broker needed

    trans

    Production Details (Flow Chart)

    1. Sourcing and Harvesting
    2. Extraction
    3. Concentration and Purification
    4. Drying
    5. Standardization
    6. Quality Control
    7. Packaging   8. Distribution

    extract process 001

    Certification

    It is certified by ISO, HALAL, and KOSHER certificates.

    CE

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