Corydalis Extract Tetrahydropalmatine (dl-THP)
Tetrahydropalmatine (THP), also known as dl-THP, Corydalin hydrochloride, or Corydalin Tube Extract, is a compound classified as an isoquinoline alkaloid. It is extracted from the tuber of the Chinese herb Corydalis yanhusuo. THP is a colorless or pale yellow crystalline substance with a slightly bitter taste and a melting point of 147-149°C. It is practically insoluble in water but highly soluble in ether, chloroform, and ethanol. Its hydrochloride and sulfate salts are soluble in water.
THP has been studied for various pharmacological effects, including its analgesic, anesthetic, neuroprotective, antiplatelet aggregation, antiulcer, antitumor, and anti-addiction properties. It is believed to exert its analgesic effects by modulating central dopamine receptor activity and has shown potential in protecting neurons from ischemic injury. Additionally, THP has demonstrated antiplatelet aggregation effects and has been investigated for its potential in treating ulcers, inhibiting tumor cell growth, and aiding in drug addiction.
Overall, Tetrahydropalmatine (dl-THP) is a compound with diverse pharmacological properties and has been the subject of extensive research for its potential therapeutic applications. For more information contact grace@biowaycn.com.
Here are the product features of Tetrahydropalmatine (THP) along with their health benefits:
1. Analgesic Properties: THP exhibits analgesic effects by modulating central dopamine receptor activity, providing pain relief without significant addictive potential.
2. Neuroprotective Effects: THP has shown potential in protecting neurons from ischemic injury, reducing neuronal apoptosis, and lowering glutamate levels in the brain, which may contribute to its neuroprotective properties.
3. Antiplatelet Aggregation: THP has been found to inhibit platelet aggregation, potentially reducing the risk of blood clot formation and related cardiovascular events.
4. Gastric Health Support: THP has demonstrated anti-ulcer effects and may help in reducing gastric acid secretion, providing relief from gastric ulcers and related conditions.
5. Potential Antitumor Activity: THP has shown cytotoxic effects on tumor cells, suggesting a potential role in inhibiting tumor growth.
6. Anti-Addiction Properties: THP has been studied for its potential to alleviate withdrawal symptoms associated with opioid and stimulant addiction, offering promise in addiction treatment and relapse prevention.
These features highlight the diverse health benefits and potential therapeutic applications of Tetrahydropalmatine (THP).
Tetrahydropydalin (dl-THP) belongs to the isoquinoline alkaloids and is an alkaloid, mainly in the genus Corydalis lucidum (Yan Hu Suo), but also in other plants such as Stephania rotunda. These plants have traditional uses in Chinese herbal medicine. Corydalis is a perennial herbaceous plant, 10 to 20 cm tall, with spherical tubers. Its above-ground stems are short and slender, with a scale above the base. Basal leaves and cauline leaves are similar in shape, with stalks; cauline leaves are alternate, with 2 and 3 compound leaves. The second leaf often splits incompletely and is deeply lobed. The small leaves are oblong, oval, or oval. Linear, about 2 cm long, with blunt or sharp apex and neat edges. Its inflorescence is raceme-shaped, with terminal or opposite leaves; the bracts are broadly lanceolate; the flowers are reddish-purple and grow horizontally on slender pedicels, which are about 6 mm long; the calyx falls early; the petals are 4 and the outer whorls are 2 The segments are slightly larger, with pink edges and bluish-purple center. There is one upper segment, and the tail extends into a long spur. The spur length accounts for about half of the total length. The inner 2 segments are narrower than the outer 2 segments. The upper end is bluish-purple and healed, and the lower segment is pink; The stamens are 6, and the filaments are connected into two bundles, each with 3 anthers; the ovary is flat-cylindrical, the style is short and thin, and the stigma is 2, like a small butterfly. Its fruit is a capsule. Corydalis is mainly produced in mountains or grasslands. The main producing areas include Zhejiang, Hebei, Shandong, Jiangsu, and other places.
Analysis | Specification |
Assay | Tetrahydropalmatine ≥98% |
Appearance | Light yellow powder to white Powder |
Ash | ≤0.5% |
Moisture | ≤5.0% |
Pesticides | Negative |
Heavy metals | ≤10ppm |
Pb | ≤2.0ppm |
As | ≤2.0ppm |
Odor | Characteristic |
Particle size | 100%through 80 mesh |
Microbiological : | |
Total of bacteria | ≤1000cfu/g |
Fungi | ≤100cfu/g |
Salmgosella | Negative |
Coli | Negative |
Here are the product application industries of Tetrahydropalmatine (THP):
1. Pharmaceuticals: THP is used in the pharmaceutical industry for developing pain management medications and neuroprotective drugs.
2. Nutraceuticals: THP is utilized in the nutraceutical industry for formulating supplements targeting pain relief and gastric health support.
3. Biotechnology: THP finds applications in biotechnology for research into antiplatelet therapies and potential cancer treatment adjuncts.
4. Healthcare: THP is incorporated into healthcare products for managing addiction and withdrawal symptoms associated with opioid and stimulant use.
5. Cosmeceuticals: THP is explored in cosmeceuticals for potential skin health and anti-inflammatory applications.
These industries demonstrate the diverse potential applications of Tetrahydropalmatine (THP) in various product development and research contexts.
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Under 100kg, 3-5Days
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