Licorice Extract Glabridin Powder(HPLC98%Min)
Licorice Extract Glabridin Powder (HPLC 98% Min) is a natural whitening agent derived from licorice flavonoids. It is extracted from the roots of Glycyrrhiza glabra Linne, and is natural, free from contamination, and has no adverse effects on the human body. It is a reddish-brown powder at room temperature, insoluble in water, but easily soluble in organic solvents such as ethanol, propylene glycol, and 1,3-butylene glycol.
Glabridin has demonstrated significant potential in drug development and medicine due to its diverse biological properties. These include anti-inflammatory, antioxidant, anti-tumor, antimicrobial, bone protection, and cardiovascular protection effects. Its multifaceted properties make it a valuable compound for potential therapeutic applications in various medical and pharmaceutical fields.
In cosmetics, licorice extract, particularly Glabridin, is valued for its whitening, anti-inflammatory, antibacterial, and antioxidant properties, making it a highly valuable cosmetic ingredient. Glabridin is highly regarded for its efficient inhibition of reactive oxygen species and melanin, earning it the nickname “whitening gold.” Its high cost and efficacy have led only a few brands to use it as a whitening component. Contact us for more information: grace@biowaycn.com.
| Product Name | Glabridin CAS 59870-68-7 |
| Appearance | White powder |
| Assay | 98% min |
| Test | HPLC |
| Certificate | ISO 9001 |
| Storage | Cool Dry Place |
| ANALYSIS | SPECIFICATION |
| Appearance | Light brown powder (White Powder for 90% 98%) |
| Assay(HPLC) | ≥40% 90% 98% |
| Loss on Drying | ≤3.0% |
| Residue on Ignition | ≤0.1% |
| Heavy Metal | <10ppm |
| Pesticide residue | Eur.ph.2000 |
| Solvent Residue | Enterprise standard |
| As | <2ppm |
| Total Plate Count | <1000cfu/g |
| Yeast & Mold | <100cfu/g |
| E.Coli | Negative |
| Salmonella | Negative |
| Other Related Product Names | Specification/CAS | Appearance |
| Licorice extract | 3:1 | Brown powder |
| Glycyrrhetnic acid | CAS471-53-4 98% | White powder |
| Dipotassium Glycyrrhizinate | CAS 68797-35-3 98%uv | White powder |
| Glycyrrhizic acid | CAS1405-86-3 98% UV; 5%HPLC | White powder |
| Glycyrrhizic Flavone | 30% | Brown powder |
| Glabridin | 90% 40% | White powder, Brown powder |
Here are the product advantages of natural Glabridin Powder (HPLC98%Min, Glycyrrhiza glabra extract) in the cosmetics field:
1. Skin Whitening: Effective for skin whitening and brightening, making it a valuable ingredient in skin lightening and brightening products.
2. Anti-Pigmentation: Helps in reducing pigmentation and dark spots, contributing to a more even skin tone.
3. Anti-Inflammatory: Exhibits anti-inflammatory properties, beneficial for soothing and calming sensitive or irritated skin.
4. Antioxidant Effects: Demonstrates potent antioxidant effects, protecting the skin from environmental stressors and promoting overall skin health.
5. Antibacterial Properties: Offers antibacterial benefits, making it suitable for skincare products targeting acne and blemish-prone skin.
6. Natural Origin: Derived from Glycyrrhiza glabra extract, ensuring a natural and authentic source for clean beauty formulations.
Natural Glabridin Powder (HPLC 98% Min) is known to have several potential health benefits, including:
Anti-inflammatory properties;
Antioxidant effects;
Potential skin whitening and brightening properties;
Anti-microbial properties;
Potential anti-tumor properties;
Glabridin works through multiple mechanisms:
001 Glabridin is a flavonoid structure with biological activity. Its main whitening and antioxidant groups can inhibit the activity of tyrosinase, thereby reducing the production of melanin. In addition, its 8-prenylated 9 structure can increase the biocompatibility of glabridin, making it easier to penetrate cell membranes or LDL particles and enter skin cells.
002 Inhibit tyrosinase activity: Tyrosinase is the key enzyme that catalyzes the conversion of tyrosine into melanin. Glycyrrhizin inhibits tyrosinase activity and reduces melanin production.
003 Inhibit dopachrome tautase activity: Dopachrome tautase regulates the production rate of melanin molecules and affects the size, type and structure of melanin. Glycyrrhizin inhibits the activity of dopachrome tautase and reduces the production of melanin.
004 Reduce reactive oxygen species: Glycyrrhizin has strong reducing properties and can reduce the generation of reactive oxygen species in cells, thereby reducing skin damage and pigmentation.
005 Reduce PIH: Glycyrrhizin has a soothing effect, can reduce skin pigmentation (PIH) caused by irritation, and will not cause anti-darkness after long-term use.
These mechanisms make glabridin a mild and safe whitening ingredient that does no harm to skin cells and can comprehensively reduce melanin production.
Here’s a simple list of industries where Glabridin Powder (HPLC 98% Min) finds application:
1. Cosmetics and Skincare:
(1) Skin Care Products: Suitable for use in skin whitening creams, serums, and lotions to promote a brighter and more even skin tone.
(2) Anti-Pigmentation Formulations: Ideal for products targeting dark spots, hyperpigmentation, and uneven skin tone.
(3) Anti-Aging Cosmetics: Valuable ingredient for anti-aging products due to its antioxidant properties and potential to promote skin health.
(4) Acne Treatment Formulations: Beneficial for acne treatment products due to its antibacterial and anti-inflammatory properties.
(5) Sun Care Products: Suitable for inclusion in sunscreens and after-sun products to help protect and soothe the skin.
(6) Clean Beauty Formulations: Ideal for natural and clean beauty products due to its natural origin and beneficial properties.
2. Pharmaceutical and Medicine;
3. Nutraceuticals and Dietary Supplements.
Packaging And Service
Packaging
* Delivery Time: Around 3-5 workdays after your payment.
* Package: In fiber drums with two plastic bags inside.
* Net Weight: 25kgs/drum,Gross Weight: 28kgs/Drum
* Drum Size & Volume: I.D.42cm × H52cm, 0.08 m³/ Drum
* Storage: Stored in a dry and cool place, keep away from strong light and heat.
* Shelf Life: Two years when properly stored.
Shipping
* DHL Express, FEDEX, and EMS for quantities less than 50KG, usually called as DDU service.
* Sea shipping for quantities over 500 kg; and air shipping is available for 50 kg above.
* For high-value products, please select air shipping and DHL express for safety.
* Please confirm if you can make the clearance when goods reach your customs before placing an order. For buyers from Mexico, Turkey, Italy, Romania, Russia, and other remote areas.
Payment And Delivery Methods
Express
Under 100kg, 3-5Days
Door to door service easy to pick up the goods
By Sea
Over300kg, Around 30 Days
Port to port service professional clearance broker needed
By Air
100kg-1000kg, 5-7Days
Airport to airport service professional clearance broker needed
Production Details (Flow Chart)
1. Sourcing and Harvesting
2. Extraction
3. Concentration and Purification
4. Drying
5. Standardization
6. Quality Control
7. Packaging 8. Distribution
Certification
It is certified by ISO, HALAL, and KOSHER certificates.
FAQ (Frequently Asked Questions)
Q: Is licorice extract safe to take?
A: Licorice extract can be safe when consumed in moderate amounts, but it’s important to be aware of potential risks and considerations. Licorice contains a compound called glycyrrhizin, which can lead to health issues when consumed in large quantities or over an extended period. These issues may include high blood pressure, low potassium levels, and fluid retention.
It’s advisable to consult with a healthcare professional before taking licorice extract, especially if you have pre-existing medical conditions, are pregnant, or are taking medications. Additionally, it’s essential to follow recommended dosages and guidelines provided by healthcare providers or product labels.
Q: Is licorice extract safe to take?
A: Licorice extract can be safe when consumed in moderate amounts, but it’s important to be aware of potential risks and considerations. Licorice contains a compound called glycyrrhizin, which can lead to health issues when consumed in large quantities or over an extended period. These issues may include high blood pressure, low potassium levels, and fluid retention.
It’s advisable to consult with a healthcare professional before taking licorice extract, especially if you have pre-existing medical conditions, are pregnant, or are taking medications. Additionally, it’s essential to follow recommended dosages and guidelines provided by healthcare providers or product labels.
Q: What medications does licorice interfere with?
A: Licorice can interact with several medications due to its potential to affect the body’s metabolism and excretion of certain drugs. Some of the medications that licorice may interfere with include:
Blood Pressure Medications: Licorice can lead to increased blood pressure and may reduce the effectiveness of medications used to lower blood pressure, such as ACE inhibitors and diuretics.
Corticosteroids: Licorice may enhance the effects of corticosteroid medications, potentially leading to an increased risk of side effects associated with these drugs.
Digoxin: Licorice may reduce the excretion of digoxin, a medication used to treat heart conditions, leading to increased levels of the drug in the body.
Warfarin and other Anticoagulants: Licorice may interfere with the effects of anticoagulant medications, potentially affecting blood clotting and increasing the risk of bleeding.
Potassium-depleting Diuretics: Licorice can lead to reduced potassium levels in the body, and when combined with potassium-depleting diuretics, it may further lower potassium levels, leading to potential health risks.
It’s crucial to consult with a healthcare professional, such as a doctor or pharmacist, before using licorice products, especially if you are taking any medications, to ensure there are no potential interactions or adverse effects.
Q: What are the health benefits of Isoliquiritigenin in dietary supplement?
A: Isoliquiritigenin is a dietary supplement that has been shown to have several potential health benefits. These include:
Reducing inflammation
Improving heart health
Protecting against certain types of cancer
Antioxidant activity
Anti-inflammatory activity
Antiviral activity
Antidiabetic activity
Antispasmodic activity
Antitumor activity
Isoliquiritigenin also has pharmacological activities against neurodegenerative diseases (NDDs). These include: Neuroprotection against brain glioma and Activity against HIV-1-associated neurocognitive disorders.
As a dietary supplement, one tablet should be taken daily. Isoliquiritigenin should be stored in a cool, dry place away from direct sunlight and heat.
