Magnolia Bark Extract Magnolol And Honokiol Powder
Magnolia Bark Extract is derived from the bark of the Magnolia officinalis tree, a plant native to China. The active ingredients in the extract are honokiol and magnolol, which possess anti-inflammatory, antioxidant, and anti-anxiety properties. The extraction process involves grinding the bark into a fine powder and then using a solvent to isolate the active compounds. Magnolia bark extract is commonly used in traditional Chinese medicine to alleviate stress, anxiety, and depression. It is also utilized in modern herbal medicine and skincare products for its calming and anti-aging effects. Additionally, it has potential applications in the treating neurodegenerative diseases and cancer, for more information contact grace@biowaycn.com.
| Items | Plant Extraction Natural Source | Chemical Synthesis |
| History | In the 1930s, Japanese scholar Yoshio Sugii first isolated magnolol from magnolia bark. | Initially synthesized by Swedish scientists H. Erdtman and J. Runebeng from allylphenol through coupling reactions. |
| Advantages | Sourced from plants, high purity. | Simple and efficient reaction process, low cost, protects magnolia resources. |
| Disadvantages | Severe damage to natural resources, labor-intensive. | Excessive residual organic solvents, chemical waste discharge, serious chemical pollution. |
| Improvement | Magnolia leaves also contain magnolol and honokiol, albeit in lower quantities. As the leaves are abundant, extracting magnolol from them protects magnolia resources and is cost-effective. | Production of magnolol through fermentation by endophytic fungi, suitable for large-scale production in fermenters. |
Anti-inflammatory properties: Magnolia bark extract contains compounds that can help reduce inflammation in the body.
Anxiolytic effects: It has been shown to have calming and anxiety-reducing effects.
Antioxidant activity: The extract contains antioxidants that can help protect cells from damage caused by free radicals.
Anti-microbial properties: It has been found to have antimicrobial effects against certain bacteria and fungi.
Neuroprotective effects: Magnolia bark extract may help protect the brain and nervous system from damage.
Anti-allergic properties: It has been shown to reduce allergic reactions potentially.
Anti-cancer potential: Some studies suggest that the extract may have anti-cancer properties, although more research is needed.
Natural Preservative: Functions as a plant-based preservative in cosmetics.
Dietary supplements: Magnolia bark extract is commonly used in dietary supplements for its potential health benefits.
Cosmetics and skincare: It is used in skincare products for its anti-inflammatory and antioxidant properties, which can help improve skin health.
Traditional medicine: In some cultures, Magnolia bark extract is used in traditional medicine for its various therapeutic properties.
Food and beverage: It may be used as a natural ingredient in certain food and beverage products for its potential health-promoting effects.
Pharmaceutical industry: The extract is being researched for its potential applications in pharmaceutical products for various health conditions.
| Items | Specification |
| Assay | ≥98.00% |
| Color | White fine powder |
| Odor | Characteristic |
| Taste | Characteristic |
| Extract Solvent | Water & Ethanol |
| Part used | Bark |
| Physical Characteristics | |
| Particle Size | 98% through 80 mesh |
| Moisture | ≤1.00% |
| Ash content | ≤1.00% |
| Bulk density | 50-60g/100ml |
| Solvent Residue | Eur. Pharm |
| Pesticide Residue | Conforms |
| Heavy Metals | |
| Heavy metals | ≤10ppm |
| Arsenic | ≤2ppm |
| Plumbum | ≤2ppm |
| Microbiological Tests | |
| Total Plate count | ≤1000cfu/g |
| Yeast & mold | ≤100cfu/g |
| Escherichia coli | Negative |
| Staphylococcus | Negative |
| Salmonella | Negative |
| Table 2: Pharmacological Research of Magnolol in Cosmetics | ||
| Test Item | Concentration | Effect Description |
| Elimination of Hydroxyl Free Radicals | 0.2mmol/L | Elimination rate: 81.2% |
| Inhibition of Peroxidation of Unsaturated Fatty Acids | 0.2mmol/L | Inhibition rate: 87.8% |
| Inhibition of Tyrosinase Activity | 0.01% | Inhibition rate: 64.2% |
| Activation of Peroxisome Proliferator-Activated Receptors (PPAR) | 100μmol/L | Activation rate: 206 (blank 100) |
| Inhibition of Nuclear Factor NF-kB Cell Activity | 20μmol/L | Inhibition rate: 61.3% |
| Inhibition of IL-1 Production Induced by LPS | 3.123mg/mL | Inhibition rate: 54.9% |
| Inhibition of IL-6 Production Induced by LPS | 3.123mg/mL | Inhibition rate: 56.3% |
| Table 3: Pharmacological Research of Honokiol in Cosmetics | ||
| Test Item | Concentration | Effect Description |
| Elimination of Hydroxyl Free Radicals | 0.2mmol/L | Elimination rate: 82.5% |
| Elimination of DPPH Free Radicals | 50μmol/L | Elimination rate: 23.6% |
| Inhibition of Peroxidation of Unsaturated Fatty Acids | 0.2mmol/L | Inhibition rate: 85.8% |
| Inhibition of Tyrosinase Activity | 0.01% | Inhibition rate: 38.8% |
| Inhibition of Nuclear Factor NF-kB Cell Activity | 20μmol/L | Inhibition rate: 20.4% |
| Inhibition of Matrix Metalloproteinase-1 (MMP-1) Activity | 10μmol/L | Inhibition rate: 18.2% |
| Additional Information: | ||
| Magnolol can be used as a preservative in cosmetics and in toothpaste and mouthwash for treating periodontitis (recommended addition in oral products is 0.4%). | ||
| Magnolol can be used in skincare products such as creams, lotions, essences, and masks. | ||
| Both magnolol and honokiol are widely used in cosmetics and other personal care products: | ||
| The recommended concentration in oral products (toothpaste, mouthwash) is 3%; can also be used as a plant-based preservative in cosmetics. | ||
| Used in facial essences, lotions, creams, masks, and other skincare products. | ||
Our Products are manufactured using stringent quality control measures and adhere to high standards of production processes. We prioritize the safety and quality of our product, ensuring that it meets regulatory requirements and industry certifications. This commitment to quality aims to establish trust and confidence in the reliability of our product. The general production process is as follows:
Storage: Keep in a cool, dry, and clean place, Protect from moisture and direct light.
Bulk Package: 20~25kg/drum.
Lead Time: 7 days after your order.
Shelf Life: 2 years.
Remark: Customized specifications can be achieved.
Express
Under 100kg, 3-5Days
Door to door service easy to pick up the goods
By Sea
Over300kg, Around 30 Days
Port to port service professional clearance broker needed
By Air
100kg-1000kg, 5-7Days
Airport to airport service professional clearance broker needed
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