Pure Natural Cepharanthine Powder
Pure Natural Cepharanthine Powder is a powdered form of the compound cepharanthine, which is derived from the plant Stephania cepharantha. It is a natural bisbenzylisoquinoline alkaloid and has been traditionally used in Chinese and Japanese medicine for its pharmacological properties, including antioxidant, anti-inflammatory, immunomodulatory, antitumoral, and antiviral activities.
In the context of COVID-19, cepharanthine has shown promising anti-COVID-19 activity. It has demonstrated significant inhibition of viral replication of SARS-CoV-2, the virus responsible for COVID-19. The IC50 and IC90 values for cepharanthine against SARS-CoV-2 are 1.90 µM and 4.46 µM, respectively.
Moreover, cepharanthine has been shown to reverse P-glycoprotein (P-gp) mediated multidrug resistance in K562 cells and enhance the sensitivity of anticancer drugs in xenograft mouse models. It also exhibits inhibitory effects on human liver cytochrome P450 enzymes such as CYP3A4, CYP2E1, and CYP2C9.
It is a concentrated form of the compound, which can be used for various purposes, including research, pharmaceutical development, and formulation.
The powder form allows for easy handling, measuring, and mixing of cepharanthine, making it convenient for use in different applications. It can be utilized for the development of medications, supplements, or other formulations that harness the potential therapeutic properties of cepharanthine.
Pure Natural Cepharanthine Powder is typically obtained through extraction and purification processes to ensure a high level of purity and quality. This ensures that the powder is free from impurities, contaminants, or other substances that could affect its efficacy or safety.
| Item | Specification | Test Results |
| Appearance | White powder, neutral odor, highly hygroscopic | Conforms |
| Identification | TLC: Standard solution and test solution same spot, RF | Conforms |
| Assay (Dry Basis) | 98.0%--102.0% | 98.1% |
| Specific Optical | -2.4°~ -2.8° | -2.71° |
| PH | 4.5~7.0 | 5.3 |
| Heavy Metals (As Pb) | ≤10ppm | <10ppm |
| As | ≤1ppm | Not Detected |
| Pb | ≤0.5ppm | Not Detected |
| Cd | ≤1ppm | Not Detected |
| Hg | ≤0.1ppm | Not Detected |
| Related substance | Spot not bigger than standard solution spot |
No spot |
| Residual solvent | <0.5% | Complies |
| Water Content | <2% | 0.18% |
(1) Pure Natural Cepharanthine Powder is derived from natural sources, specifically the Stephania cepharantha Hayata plant.
(2) It is a concentrated form of the compound cepharanthine, allowing for easy handling, measuring, and mixing.
(3) The powder is suitable for various purposes, including research, pharmaceutical development, and formulation.
(4) It undergoes extraction and purification processes to ensure high purity and quality, free from impurities or contaminants.
(5) It can be used for the development of medications, supplements, or other formulations harnessing the potential therapeutic properties of cepharanthine.
(1) Pure Natural Cepharanthine Powder has been shown to possess potent antioxidant properties, scavenging free radicals and reducing oxidative stress.
(2) It exhibits anti-inflammatory effects, which can help alleviate symptoms associated with inflammation-related conditions.
(3) Cepharanthine has been studied for its potential antimicrobial activity, showing efficacy against various bacterial and fungal strains.
(4) It may have anti-viral properties and has been explored for its potential antiviral activity against certain viruses.
(5) Cepharanthine has been found to have immune-modulating effects, potentially enhancing the immune system's response.
(6) Studies suggest that it may have anticancer properties, inhibiting the growth and spread of cancer cells in various types of cancers.
(7) It has been investigated for its potential cardiovascular benefits, such as improving blood flow and supporting heart health.
(8) Cepharanthine may have neuroprotective effects, potentially offering support for neurological conditions.
It shows promise in the field of dermatology, potentially having skin-protective and wound-healing properties.
(1) Pharmaceutical industry
(2) Nutraceuticals and dietary supplements
(3) Cosmetics and skincare
(4) Traditional medicine
(5) Research and development
(1) Plant cultivation: The raw material, Stephania cepharantha plants, are grown in suitable agricultural conditions.
(2) Harvesting: The mature plants are carefully hand-picked to ensure quality.
(3) Drying: The harvested plants are dried using traditional methods or modern techniques to remove moisture.
(4) Extraction: The dried plant material is pulverized into a fine powder and subjected to extraction using solvents like ethanol or water.
(5) Filtration: The extract is filtered to remove impurities and obtain a clear solution.
(6) Concentration: The filtrate is concentrated to remove excess solvent and increase the concentration of Cepharanthine.
(7) Purification: The concentrated extract undergoes further purification processes like chromatography or crystallization to obtain pure Cepharanthine.
(8) Drying: The purified Cepharanthine is dried to remove any residual moisture.
(9) Powdering: The dried Cepharanthine is pulverized into a fine powder.
(10) Quality control: The powder is subjected to rigorous testing to ensure it meets the quality standards for purity, potency, and safety.
(11) Packaging: The final product is packaged in airtight containers to preserve its quality and shelf life.
(12) Storage: The packaged Cepharanthine powder is stored in suitable conditions to maintain its stability and efficacy.
Note: The actual production process may vary depending on the manufacturer and specific requirements.
Storage: Keep in a cool, dry, and clean place, Protect from moisture and direct light.
Bulk Package: 25kg/drum.
Lead Time: 7 days after your order.
Shelf Life: 2 years.
Remark: Customized specifications also can be achieved.
20kg/bag 500kg/pallet
Reinforced packaging
Logistics security
Express
Under 100kg, 3-5Days
Door to door service easy to pick up the goods
By Sea
Over300kg, Around 30 Days
Port to port service professional clearance broker needed
By Air
100kg-1000kg, 5-7Days
Airport to airport service professional clearance broker needed
Pure Natural Cepharanthine Powder is certified with the ISO certificate, HALAL certificate, and KOSHER certificate.
The side effects of Pure Natural Cepharanthine Powder can vary from person to person and may not be experienced by everyone. Some potential side effects that have been reported include:
Gastrointestinal Issues: Some individuals may experience gastrointestinal discomfort, such as nausea, stomach pain, diarrhea, or constipation.
Allergic Reaction: In rare cases, an allergic reaction may occur, resulting in symptoms like skin rash, itching, swelling, or difficulty breathing. If you experience any allergic reactions, discontinue use and seek medical attention immediately.
Blood Pressure and Heart Rate: Cepharanthine may have an impact on blood pressure and heart rate. Individuals with pre-existing cardiovascular conditions or those taking medications for blood pressure regulation should exercise caution and consult their healthcare professional before using Cepharanthine.
Interactions with Medications: Cepharanthine may interact with certain medications, such as anticoagulants or antiplatelet drugs. These interactions could affect blood clotting or increase the risk of bleeding. It is essential to inform your healthcare professional about all medications you are taking before using Cepharanthine.
Other Potential Side Effects: While there are limited studies on the specific side effects of Cepharanthine, some users have reported experiencing sleep disturbances, dizziness, headaches, or changes in appetite.
It is crucial to note that the above side effects are not exhaustive, and individual experiences may vary. If you experience any concerning or persistent side effects while taking Cepharanthine, it is important to seek medical attention and consult with a healthcare professional.
