Vinca Rosea Extract Vincristine
Vinca Rosea Extract Vincristine refers to the pharmaceutical compound Vincristine, which is derived from the periwinkle plant (Vinca rosea), which is also known as Catharanthus roseus, bright eyes, Cape periwinkle, graveyard plant, Madagascar periwinkle, old maid, pink periwinkle, rose periwinkle, is a perennial species of flowering plant in the family Apocynaceae.
Vincristine is a natural alkaloid and is used as a chemotherapy medication to treat various types of cancer, including leukemia, lymphoma, and solid tumors. It works by disrupting the growth of cancer cells.
| Main Active Ingredients in Chinese | English Name | CAS No. | Molecular Weight | Molecular Formula |
| 长春胺 | Vincamine | 1617-90-9 | 354.44 | C21H26N2O3 |
| 脱水长春碱 | Anhydrovinblastine | 38390-45-3 | 792.96 | C46H56N4O8 |
| 異長春花苷內酰胺 | Strictosamide | 23141-25-5 | 498.53 | C26H30N2O8 |
| 四氢鸭脚木碱 | Tetrahydroalstonine | 6474-90-4 | 352.43 | C21H24N2O3 |
| 酒石酸长春瑞滨 | Vinorelbine Tartrate | 125317-39-7 | 1079.12 | C45H54N4O8.2(C4H6O6);C |
| 长春瑞滨 | Vinorelbine | 71486-22-1 | 778.93 | C45H54N4O8 |
| 长春新碱 | Vincristine | 57-22-7 | 824.96 | C46H56N4O10 |
| 硫酸长春新碱 | Vincristine sulfate | 2068-78-2 | 923.04 | C46H58N4O14S |
| 硫酸长春质碱 | Catharanthine Sulfate | 70674-90-7 | 434.51 | C21H26N2O6S |
| 酒石酸长春质碱 | Catharanthine hemitartrate | 4168-17-6 | 486.51 | C21H24N2O2.C4H6O6 |
| 长春花碱 | Vinblastine | 865-21-4 | 810.99 | C46H58N4O9 |
| 长春质碱 | Catharanthine | 2468-21-5 | 336.43 | C21H24N2O2 |
| 文朵灵 | Vindoline | 2182-14-1 | 456.53 | C25H32N2O6 |
| 硫酸长春碱 | Vinblastine Sulfate | 143-67-9 | 909.05 | C46H60N4O13S |
| β-谷甾醇 | β-Sitosterol | 83-46-5 | 414.71 | C29H50O |
| 菜油甾醇 | Campesterol | 474-62-4 | 400.68 | C28H48O |
| 齐墩果酸 | Oleanolic acid | 508-02-1 | 456.7 | C30H48O3 |
| PRODUCT SPECIFICATIONS | ||
| Product Name: | Vinca rosea extact | |
| Botanic Name: | Catharanthus roseus (L.) | |
| Part of plant | Flower | |
| Country of Origin: | China | |
| ANALYSIS ITEMS | SPECIFICATION | TEST METHOD |
| Appearance | Fine powder | Organoleptic |
| Color | Brown fine powder | Visual |
| Odour & Taste | Characteristic | Organoleptic |
| Identification | Identical to R.S. sample | HPTLC |
| Extract Ratio | 4:1~20:1; Vincristine 98%min | |
| Sieve Analysis | 100% through 80 mesh | USP39 <786> |
| Loss on drying | ≤ 5.0% | Eur.Ph.9.0 [2.5.12] |
| Total Ash | ≤ 5.0% | Eur.Ph.9.0 [2.4.16] |
| Lead (Pb) | ≤ 3.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Arsenic (As) | ≤ 1.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Cadmium(Cd) | ≤ 1.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Mercury(Hg) | ≤ 0.1 mg/kg -Reg.EC629/2008 | Eur.Ph.9.0<2.2.58>ICP-MS |
| Heavy metal | ≤ 10.0 mg/kg | Eur.Ph.9.0<2.4.8> |
| Solvents Residue | Conform Eur.ph. 9.0 <5,4 > and EC European Directive 2009/32 | Eur.Ph.9.0<2.4.24> |
| Pesticides Residues | Conform Regulations(EC) No.396/2005including annexes and successive updates
Reg.2008/839/CE |
Gas Chromatography |
| Aerobic bacteria(TAMC) | ≤10000 cfu/g | USP39 <61> |
| Yeast/Moulds(TAMC) | ≤1000 cfu/g | USP39 <61> |
| Escherichia coli: | Absent in 1g | USP39 <62> |
| Salmonella spp: | Absent in 25g | USP39 <62> |
| Staphylococcus aureus: | Absent in 1g | |
| Listeria Monocytogenens | Absent in 25g | |
| Aflatoxins B1 | ≤ 5 ppb -Reg.EC 1881/2006 | USP39 <62> |
| Aflatoxins ∑ B1, B2, G1, G2 | ≤ 10 ppb -Reg.EC 1881/2006 | USP39 <62> |
The product features of Vinca Rosea Extract Vincristine may include:
High purity: Vincristine products usually have high purity and comply with strict standards for drug manufacturing to ensure the purity and stability of the drug.
Source traceability: Vincristine is usually extracted from the Catharanthus roseus plant. Its production process is traceable and complies with the collection and production specifications of botanical medicinal materials.
Chemical stability: As an alkaloid compound, vincristine has good chemical stability and is suitable for pharmaceutical production and long-term storage.
Anti-tumor activity: As an anti-tumor drug, vincristine has the activity of inhibiting the growth and spread of tumor cells and is suitable for the treatment of various cancers.
Clinical verification: Vincristine has been clinically verified and is widely used in medical practice, with reliable pharmacological and clinical effect data support.
These product characteristics highlight the quality, activity, and clinical value of vincristine as an important anti-cancer drug.
Vinca Rosea Extract Vincristine is primarily known for its pharmaceutical applications in cancer treatment and is not typically associated with direct health benefits for general consumer use. Vincristine, derived from the Vinca rosea plant, is a potent chemotherapy medication used to treat various types of cancer, including leukemia, lymphoma, and solid tumors. It works by interfering with the growth of cancer cells.
It’s important to note that Vincristine is a prescription medication administered under the supervision of healthcare professionals, and its use is associated with potential side effects and risks. Therefore, it is not typically marketed or consumed for its health benefits outside of clinical settings.
The detailed applications of Vinca Rosea Extract Vincristine include:
Cancer Treatment: Vincristine is primarily used in the treatment of various types of cancer, including leukemia, lymphoma, and solid tumors. It is administered as part of chemotherapy regimens to inhibit the growth of cancer cells.
Pharmaceutical Research: The extract is utilized in pharmaceutical research for the development of new cancer treatments and the study of its mechanism of action.
Medicinal Chemistry: Vincristine serves as a valuable compound in the field of medicinal chemistry, contributing to the development of novel drugs and therapeutic agents.
Biotechnology: The extract may be employed in biotechnological applications, such as the production of anticancer formulations and drug delivery systems.
Clinical Trials: Vincristine is involved in clinical trials to explore its efficacy in treating various forms of cancer and to investigate potential applications in other medical conditions.
Drug Formulation: The extract is used in the formulation of pharmaceutical products, including injectable solutions and other dosage forms for cancer therapy.
These applications demonstrate the diverse uses of Vinca Rosea Extract Vincristine in cancer treatment, pharmaceutical research, and drug development.
Vincristine is a potent chemotherapy medication, and its use can be associated with several potential side effects. Some of the potential side effects of Vincristine powder may include:
Neurotoxicity: Vincristine can cause damage to the peripheral nervous system, leading to symptoms such as numbness, tingling, and weakness in the extremities.
Gastrointestinal Effects: Common gastrointestinal side effects may include nausea, vomiting, constipation, and abdominal pain.
Bone Marrow Suppression: Vincristine can suppress the bone marrow, leading to decreased production of blood cells, which may result in anemia, increased susceptibility to infections, and bleeding tendencies.
Hair Loss: Some individuals may experience hair loss or thinning of the hair as a result of Vincristine treatment.
Jaw Pain: Vincristine can cause a specific type of pain known as “vincristine-induced neuropathy-acute-onset,” which is characterized by jaw pain and difficulty swallowing.
Other Potential Effects: Additional side effects may include muscle weakness, changes in blood pressure, and allergic reactions.
It’s important to note that the above list is not exhaustive, and healthcare professionals should closely monitor individuals receiving Vincristine for any potential side effects. The specific side effects and their severity can vary from person to person. Patients should discuss potential side effects and concerns with their healthcare provider before starting Vincristine treatment.
Packaging And Service
Packaging
* Delivery Time: Around 3-5 workdays after your payment.
* Package: In fiber drums with two plastic bags inside.
* Net Weight: 25kgs/drum,Gross Weight: 28kgs/Drum
* Drum Size & Volume: I.D.42cm × H52cm, 0.08 m³/ Drum
* Storage: Stored in a dry and cool place, keep away from strong light and heat.
* Shelf Life: Two years when properly stored.
Shipping
* DHL Express, FEDEX, and EMS for quantities less than 50KG, usually called as DDU service.
* Sea shipping for quantities over 500 kg; and air shipping is available for 50 kg above.
* For high-value products, please select air shipping and DHL express for safety.
* Please confirm if you can make the clearance when goods reach your customs before placing an order. For buyers from Mexico, Turkey, Italy, Romania, Russia, and other remote areas.
Payment And Delivery Methods
Express
Under 100kg, 3-5 Days
Door to door service easy to pick up the goods
By Sea
Over300kg, Around 30 Days
Port to port service professional clearance broker needed
By Air
100kg-1000kg, 5-7 Days
Airport to airport service professional clearance broker needed
Production Details (Flow Chart)
1. Sourcing and Harvesting
2. Extraction
3. Concentration and Purification
4. Drying
5. Standardization
6. Quality Control
7. Packaging 8. Distribution
Certification
It is certified by ISO, HALAL, and KOSHER certificates.
